Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Danışman Kurulu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2005, Cilt 19, Sayı 1, Sayfa(lar) 075-080
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EVALUATION OF GRAM-NEGATIVE BACILLI ISOLATED FROM INTENSIVE CARE UNITS
Özgen KÖSEOĞLU-ESER1, Sesin KOCAGÖZ2, Alper ERGİN3, Belgin ALTUN4, Gülşen HASÇELİK1
1Hacettepe Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Ankara
2Yeditepe Üniversitesi Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, İstanbul
3Hacettepe Üniversitesi Sağlık Hizmetleri Yüksekokulu, Ankara
4Hacettepe Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, İnfeksiyon Ünitesi, Ankara
Keywords: Gram-negative bacilli, nosocomial infection, intensive care unit, in vitro antimicrobial susceptibility, E test

The aim of this descriptive study was to evaluate the susceptibilities of gram-negative bacilli isolated from patients with gram-negative nosocomial infection in the General Surgery, Internal Medicine, Brain Surgery, Chest and Cardiac Surgery and Burn Intensive Care Units of the Hacettepe University Hospitals. Antibiotic susceptibilities of 11 antimicrobials were evaluated in 94 gram-negative bacilli which were isolated from 79 patients. Antibiotic susceptibility testing was performed with E-test. The percentages of specimens in which the microorganisms isolated were: 27% broncho alveolar lavage, 21% tracheal aspirate, 16% urine, 14% pus, 9% blood, 4% bile, 3% cerebrospinal fluid, 2% sputum and catheter, 1% drainage device and parasynthesis. The percentages of microorganisms isolated were; 42% Pseudomonas aeruginosa, 20% Escherichia coli, 18% Acinetobacter spp, 9% Klebsiella spp, 4% Enterobacter cloacae, 3% Stenotrophomonas maltophilia, 2% Serratia marcescens, 1% Citrobacter freundii and 1% Proteus mirabilis. The range of resistance among P. aeruginosa and Acinetobacter isolates against 11 antimicrobial agents were between 53.8 and 89.7% which showed the high level of antibiotic resistance in these isolates. Among the E. coli isolates, except for ciprofloxacin (42.1%), no resistance was found against the antimicrobial agents tested. The high level of antibiotic resistance in intensive care units is possibly due to long and improper antibiotic treatment. The antibiotic susceptibility profiles should be surveyed continuously to avoid the spread of intensive care unit isolates carrying high level antibiotic resistance for better achievement of treatment regimens.

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