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2006, Cilt 20, Sayı 2, Sayfa(lar) 131-135
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CLINICAL AND RADIOLOGICAL FINDINGS IN A CASE OF VARICELLA ENCEPHALITIS
Şevki SAHİN1, Ayşe SİVREL-ARISOY2, Aynur E. TOPKAYA3, Sibel KARŞIDAĞ1
1Maltepe Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, İstanbul
2Maltepe Üniversitesi Tıp Fakültesi, Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Anabilim Dalı, İstanbul
3Maltepe Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, İstanbul
Keywords: Varicella-Zoster Virus, Encephalitis, MRI, SPECT

The Varicella-Zoster virus infection (chicken pox) is rarely seen in adults and subjects with normal immunity, but its complications might be fatal. A 29-year-old previously healthy male patient applied to the emergency ward five days after the occurrence of chicken pox rashes with complaints of vertigo, nausea, and imbalance. Although Varicella-Zoster antibodies were found to be negative in the initial cerebrospinal fluid (CSF) and blood examinations of the patient, these antibodies were detected both in the CSF and blood of the patient on the tenth day. Right cerebellar and bilateral cerebellar hypoperfusion were determined with brain single photon emission tomography (SPECT) labelled with Tc-99m hexamethyl propylene amine oxime (HMPAO) whereas no pathologies were detected in the contrasted cranial magnetic resonance imaging (MRI). Partial clinical improvement was achieved after a 10-day antiviral therapy and an almost complete improvement was observed in the neurological examination of the patient at the third month follow up. Although the repeated cranial MRI examination performed in this period was found to be normal, in the Tc-99 HMPOA brain SPECT examination it was observed that the previously determined pathology continued to exist. In this article, the clinical and radiological findings of the case are discussed in the light of the literature.

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