A case of meningitis due to Listeria monocytogenes is presented. The patient, a 60-year-old male, receiving the prediagnosis of acute bacterial meningitis, was first treated with ceftriaxone. Upon progression of clinical findings and consideration of his family history of tuberculosis and the compatibility of cerebrospinal fluid (CSF) findings with tuberculous meningitis, anti-tuberculous treatment was implemented. An agent was isolated in his cerebrospinal fluid 24 hours after the implementation of anti-tuberculosis treatment. The agent was identified as L. monocytogenes. All of the anti-tuberculosis drugs were stopped except rifampin to which ampicillin was added. The case was cured with the combination of ampicillin and rifampin.