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2003, Cilt 17, Sayı 4, Sayfa(lar) 443-446
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INVESTIGATION OF NASAL CARRIAGE RATES AND ANTIMICROBIAL SUSCEPTIBILITY OF STAPHYLOCOCCUS AUREUS IN HEALTH-CARE WORKERS AND HEMODIALYSIS PATIENTS IN DICLE UNIVERSITY HOSPITAL
Ömer Faruk KÖKOĞLU, Mehmet Faruk GEYİK, Celal AYAZ, Hasan UÇMAK, Salih HOŞOĞLU
Dicle Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Diyarbakır
Keywords: Health-care workers, hemodialysis patients, nasal carriage, methicillin-resistant Staphylococcus aureus (MRSA)

Nasal carriage of Staphylococcus aureus among health-care workers (HCWs) is a significant risk factor for the epidemic staphylococcal infection in hospitals. With the purpose of determining the incidence of nasal carriage at Dicle University Hospital, 204 HCWs, 36 hemodialysis patients and 50 healthy controls were prospectively screened. Nasal carriage of S. aureus was found in 34 nurses (31.2%), 15 doctors (28.9%), and 17 other personnel (39.5%). In total; 66 HCWs (32.4%), 14 hemodialysis patients (38.9%), and 13 healthy controls (26.0%) were found positive. Twenty-six out of 66 HCW strains (39.4%), eight of out 14 hemodialysis (57.4%), and two of out 13 healthy controls (15.4%) methicillin-resistant S. aureus (MRSA) strains were determined. Susceptibility test was performed on 93 S. aureus strains using microdilution method. No strain of S. aureus was found resistant to vancomycin. The susceptibility rates to the antibiotics were as follows: to ofloxacin 74.2%, rifampicin 67.7%, gentamicin 63.4%, sulbactamampicillin 59.1%, tetracycline 54.8%, erythromycin 51.6%, co-trimoxazole 32.3%, cefazolin 26.9%, and clindamycin 21.5 %. All strains were resistant to penicillin G and ampicillin.

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