2007, Cilt 21, Sayı 2, Sayfa(lar) 055-058 |
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AN ENDEMIC OF TULAREMIA IN THE HAVZA-SAMSUN REGION: A RETROSPECTIVE EVALUATION OF THE CASES |
Özlem ACİCBE1, Hüseyin AYDIN2, Levent DOĞANCI3 |
1Havza Devlet Hastanesi Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Havza, Samsun 2Havza Devlet Hastanesi Kulak Burun Boğaz Hastalıkları Kliniği, Havza, Samsun 3Ondokuz Mayıs Üniversitesi Tıp Fakültesi Klinik Bakteriyoloji ve Enfeksiyon Hastalıkları Anabim Dalı, Samsun |
Keywords: Francisella tularensis, tularemia, endemia |
In this study, 75 cases of tularemia at Havza-Samsun region were evaluated retrospectively between January 2005 to February
2007. The disease has a seasonal pattern and has become most frequent in November through March. Of the patients, 42 (56%)
were female and 33 (44%) were male. Mean age was 42 (3-75) and 94% were age of 18 and above. All of cases exhibit oropharyngeal
form of tularemia. Antibodies against F. tularensis were detected in 35 (54%) of 65 patients with the microagglutination test,
and 28 of them had 1/160 and higher titers. So far, 30 patients (46%) were seronegative. White blood cell counts were within the
normal limits and mean erythrocyte sedimentation rate was 58 mm/h. The patients received daily administration of 1. g of streptomycine
for 14 days. Of the 75 patients, 21 (%28) underwent surgical drainage. The cases illustrate how mode of acquisition (direct
water-borne versus tick-mediated) influences the clinical form (orophyrengeal) of the disease. In addition, a brief review of the epidemiology,
differential diagnosis, clinical manifestations, and treatment of tularemia is discussed.
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