The purpose of this study was to investigate the anticandidal activity of Pseudomonas aeruginosa strains. The in vitro anticandidal activity of 120 Pseudomonas aeruginosa strains isolated from various clinical specimens against Candida species was investigated. Candida albicans ATCC 90028, Candida parapsilosis ATCC 90018 and Candida glabrata ATCC 90030 were used as Candida strains and anticandidal activity of P. aeruginosa strains was examined by using Kerr's method on blood agar and Sabourauddextrose- agar (SDA). Having no growth of Candida strains was considered as total inhibition and the decrease of growth compared to the control was accepted as partial inhibition. Total inhibition rates against C. albicans, C. parapsilosis and C. glabrata obtained by using blood agar were 54.1%, 51.6% and 50%, respectively. When SDA was used, the rates were detected as 52.5%, 49.1% and 48.3%, respectively. In conclusion, in most strains of P. aeruginosa an anticandidal activity was detected. The clinical implic - ations of this activity was discussed.