A seventeen-month-old girl was admitted to hospital with the complaints of high fever, swelling in the whole left leg and echimotic lesions on anterior side of the upper part of the left leg. In history she had been diagnosed to have varicella six days before the hospitalization. On physical examination there were many small petechial and purpuric hemorrages and various sized echimotic and necrotic lesions over the skin covering the buttocks and both legs. The lesions were more marked on the left leg. Protein C, protein S and antithrombine III levels were low and anticardiolipin antibodies were high. Thus the diagnosis of varicella associated purpura fulminans was established. Antibiotherapy, fresh frozen plasma and low molecular weight heparine therapies were given. On the 7th day of hospitalization, d-dimer and the tests of haemorhagic diatesis were normal but protein C, protein S and antithrombine III levels were still low. Because the necrotic lesions on the left leg progressed to the osseos tissue, she was referred to the Plastic Surgery Center for debridment and grafting on the 8th day of hospitalization. Protein C, protein S and antithrombine III levels were found normal after the patient improved.