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2006, Cilt 20, Sayı 3, Sayfa(lar) 165-170
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THE NOSOCOMIAL INFECTIONS, MICROORGANISMS AND THEIR ANTIMICROBIAL SUSCEPTIBILITIES AND ANTIBIOTIC CONSUMPTION IN INTENSIVE CARE UNIT
Burçin ÖZER1, Müşerref TATMAN-OTKUN2, Dilek MEMİŞ3, Metin OTKUN2
1Mustafa Kemal Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Hatay
2Trakya Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Edirne
3Trakya Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Edirne
Keywords: Antibiotic consumption, intensive care unit, nosocomial infection, antimicrobial resistance

The aim of this study was to determine the antibiotics used in the Intensive Care Unit (ICU) of Trakya University Hospital, their effect on the microorganisms isolated as nosocomial infection agents and the relation between the antibiotic consumption and hospital infections. The patients hospitalized in ICU were evaluated prospectively with the active surveillance method based on the labor-atory and patients. The identification of microorganisms and antimicrobial susceptibilities tests were made the in Microbiology Laboratory of Trakya University Hospital. Thirty six Acinetobacter spp, 25 Pseudomonas aeruginosa, one Stenotrophomonas maltophilia, 20 Candida spp, eight bacteria belonging to Enterobectericeae, 25 Staphylococcus spp, five Enterococcus spp, in total 120 microorganisms were isolated. The most effective antibiotic against Acinetobacter spp. was cefoperasone/sulbactam, and to P. aeruginosa piperacillin/tazobactam and meropenem. The vancomycin resistance was not detected in gram positive bacteria, but 85% of Staphylococcus aureus strains were resistant to meticilline. No relation between the antibiotic usage and nosocomial infections was found. The antibiotics should be used in appropriate dosage and for appropriate periods, the combination of appropriate antibiotics according to the ICUs’ flora should be used in empiric treatment and the treatment should be rearranged according to the reports of cultures. The antibiotics should be given following consultation with infectious disease specialists.

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