2007, Cilt 21, Sayı 3, Sayfa(lar) 117-122 |
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THE EVALUATION OF CASES OF TUBERCULOUS MENINGITIS |
Meltem AVCI1, Onur ÖZGENÇ1, Alpay ARI1, Gülşen MERMUT1, Ayten COŞKUNER1, Ziya KURUÜZÜM2, Serap SEVİM1, Şenay ÖZTÜRK1 |
1Sağlık Bakanlığı İzmir Eğitim Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, İzmir 2Dokuz Eylül Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İzmir |
Keywords: Tuberculous meningitis, adults, clinical picture |
Thirty-three adult cases of tuberculous meningitis hospitalized in the Clinic of Infectious Diseases, Izmir Teaching Hospital, İzmir
between 1996-2002 were evaluated with respect to history, clinical and laboratory findings, treatment and prognosis. The mean age
of the patients was 39±16 years with a range of 16 to 70. Almost all the patients had fever, headache, nausea and vomiting. On
physical examination meningial irritation findings (100%), alteration of consciousness (82%), diplopi (24%), strabismus (12%), facial
paralysis and hemiparesis (9%) were observed. Thirty percent of the cases were diagnosided to have active pulmonary
tuberculosis. The confirmation of the diagnosis was made through cererospinal fluid (CSF) examination and clinical data. Acid-fast
bacilli were isolated from CSF in 18%. Nine (27%) cases died; all were in the third stage of the disease and had underlying
diseases. One (3%) patient developed hemiparesis as sequela. In conclusion; tuberculous meningitis is associated with a high
mortality and morbidity. For this reason early diagnosis and effective treatment are important for favorable prognosis and preventing
sequelae.
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